First Name / Last Name: Michel SEVE
Title or function: PharmD, PhD, Professor in Biotechnology
Affiliation (Lab, university, company) : TIMC-IMAG UMR 5525, Université Grenoble Alpes
I am Professor at Université Grenoble Alpes and hospital biologist at Grenoble University Hospital (CHUGA). I develop for many years a research activity in the field of proteomics applied to the analysis of complex clinical samples for biomarkers and targets identification. These analytical techniques need more and more sophisticated approach to analyze the large set of data. More recently, I reach a research team working on the impact of the environment on human health and the prevention of diseases due to pollutants exposition. I develop combined biological and analytical techniques and computer sciences approach to solve the link between environmental parameters and biological disorders responsible for pathologies.
A large scale proteome analysis of the gefitinib primary resistance overcome by KDAC inhibition in KRAS mutated adenocarcinoma cells overexpressing amphiregulin.
J Proteomics. 2019 Mar 20;195:114-124.
Current trends in protein acetylation analysis.
Expert Rev Proteomics. 2019 Feb;16(2):139-159
Tubulin Beta-3 Chain as a New Candidate Protein Biomarker of Human Skin Aging: A Preliminary Study.
Oxid Med Cell Longev. 2017;2017:5140360.
Quantitative proteomic approach to understand metabolic adaptation in non-small cell lung cancer.
J Proteome Res. 2014 Nov 7;13(11):4695-704.